Efinaconazole - KP103

Based on 183 reference(s) in Google Scholar 8 10 183

Axon 3369

CAS [164650-44-6]

MF C18H22F2N4O
MW 348.39

  • Purity: 100%
  • Optical purity: Optically pure
  • Soluble in 0.1N HCl(aq) and DMSO

Efinaconazole

Description

Efinaconazole is a topical antifungal that inhibits sterol 14α-demethylase, an enzyme in the ergosterol biosynthesis pathway. Efinaconazole has lower minimum inhibitory concentrations than terbinafine, ciclopirox, itraconazole and amorolfine in Trichophyton rubrum, Trichophyton mentagrophytes and Candida albicans.

KEYWORDS: Efinaconazole | Antifungal agent | KP103 | KP 103 | KP-103 | CAS [164650-44-6] | [164650-61-7] | Steroid (Lanosterol 14-α) | Cytochrome P450 | Inhibitor | Enzymes | Onychomycosis

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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