Based on 3 reference(s) in Google Scholar 8 10 3

Axon 3340

CAS [1464151-33-4]

MF C25H20N4O2
MW 408.45

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO



ETC-206 is a potent, selective and orally available MNK1/2 inhibitor with IC50 values of 0.064 μM and 0.086 μM for MNK1 and MNK2, respectively. ETC-206 in combination with dasatinib (Axon 1392) prevents BC-CML LSC self-renewal in vitro and enhances dasatinib antitumor activity in vivo.

KEYWORDS: ETC-206 | suppliers | MNK1/2 inhibitor | ETC206 | ETC 206 | CAS [1464151-33-4] | DNA-RNA | Mnk1 | Inhibitor | Enzymes | Blast crisis chronic myeloid leukemia | BC-CML | eIF4E

Size Unit Price Stock
5 mg €130.00 In Stock
25 mg €460.00 In Stock
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Size Unit Price Stock
2 x 5 mg €200.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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