Trilostane - WIN 24540

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3317

CAS [13647-35-3]

MF C20H27NO3
MW 329.43

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO

Trilostane

Description

Trilostane is an orally active, competitive inhibitor of 3β-hydroxysteroid dehydrogenase.

GO Potts et al. Trilostane, an orally active inhibitor of steroid biosynthesis. Steroids. 1978 Sep;32(2):257-67.

P Komanicky et al. Treatment of Cushing's syndrome with trilostane (WIN 24,540), an inhibitor of adrenal steroid biosynthesis. J Clin Endocrinol Metab. 1978 Nov;47(5):1042-51.

Endocrinology EC 1.1.1.145

Orally active, competitive inhibitor of 3β-hydroxysteroid dehydrogenase

Chemical name

(1S,2R,6R,8S,11S,12S,15S,16S)-5,15-Dihydroxy-2,16-dimethyl-7-oxapentacyclo[9.7.0.02,8.06,8.012,16]octadec-4-ene-4-carbonitrile

Parent CAS No.

[13647-35-3]

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