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Milrinone
- WIN 47203- Soluble in DMSO
- MF: C12H9N3O
- MW: 211.22
Description
Milrinone is a positive inotropic phosphodiesterase III inhibitor and vasodilator agent. Milrinone inhibits the intracellular hydrolysis of cyclic AMP, thereby promoting cyclic AMP-catalysed phosphorylation of sarcolemmal calcium channels and activating the calcium pump.
More Information
| Parent CAS No. | 78415-72-2 |
|---|---|
| Chemical Name | 6-Methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridine-3-carbonitrile |
| SMILES | N1C=CC(C2C=C(C#N)C(=O)NC=2C)=CC=1 |
| MFCD | MFCD00133539 |
| InChi | InChI=1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16) |
| InChiKey | PZRHRDRVRGEVNW-UHFFFAOYSA-N |
| CID | 4197 |
| Short Description | PDE3 inhibitor |
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