Dexamethasone

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3258

CAS [50-02-2]

MF C22H29FO5
MW 392.46

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO

Dexamethasone

Description

Dexamethasone, an anti-inflammatory steroid, is a glucocorticoid receptor agonist. Dexamethasone was shown to have benefit in treatment of patients which are critically ill with COVID-19.

GE Arth et al. 16-Methylated steroids. I. 16a-Methylated analogs of cortisone, a new group of anti-inflammatory steroids. J. Am. Chem. Soc. 1958, 80, 12, 3160-3161.

H Ledford. Coronavirus breakthrough: dexamethasone is first drug shown to save lives. Nature. 2020 Jun;582(7813):469.

CA LaLone et al. Effects of a glucocorticoid receptor agonist, dexamethasone, on fathead minnow reproduction, growth, and development. Environ Toxicol Chem. 2012 Mar;31(3):611-22.

Glucocorticoid agonist

Chemical name

(8S,9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

Parent CAS No.

[50-02-2]

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Dexamethasone

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Dexamethasone

Description

Chemical name

Parent CAS No.

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