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Flunisolide
- AeroBid - Nasalide - Nasarel- Soluble in DMSO
- MF: C24H31FO6
- MW: 434.5
Description
Flunisolide is a synthetic glucocorticoid receptor agonist with anti-inflammatory activity in nasal and airway tissues.
Flunisolide reduces inflammatory-cell recruitment, vascular permeability and cytokine production through glucocorticoid-responsive transcription. It is a clinically relevant reference for allergic rhinitis, airway inflammation and corticosteroid pharmacology.
Key Features
- Synthetic glucocorticoid receptor agonist
- Suppresses local inflammatory mediator production
- Reduces allergic and airway inflammatory responses
- Established intranasal and inhaled corticosteroid pharmacology
Applications
- Glucocorticoid receptor functional assays
- Allergic rhinitis models
- Airway inflammation research
- Corticosteroid response and gene-regulation studies
More Information
| Parent CAS No. | 3385-03-3 |
|---|---|
| Chemical Name | (4aR,4bS,5S,6aS,8R,9S,10aS,12S)-12-Fluoro-5-hydroxy-6b-(2-hydroxy-acetyl)-4a,6a,8,8-tetramethyl-4a,4b,5, 6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one |
| MFCD | MFCD00133324 |
| Short Description | Corticosteroid |
References
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