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Flunisolide

 - AeroBid  - Nasalide  - Nasarel
Axon 1429
CAS:  3385-03-3
Purity:  99%
  • Soluble in DMSO
  • MF:  C24H31FO6
  • MW:  434.5

Description

Flunisolide is a synthetic glucocorticoid receptor agonist with anti-inflammatory activity in nasal and airway tissues.

Flunisolide reduces inflammatory-cell recruitment, vascular permeability and cytokine production through glucocorticoid-responsive transcription. It is a clinically relevant reference for allergic rhinitis, airway inflammation and corticosteroid pharmacology.

Key Features

  • Synthetic glucocorticoid receptor agonist
  • Suppresses local inflammatory mediator production
  • Reduces allergic and airway inflammatory responses
  • Established intranasal and inhaled corticosteroid pharmacology

Applications

  • Glucocorticoid receptor functional assays
  • Allergic rhinitis models
  • Airway inflammation research
  • Corticosteroid response and gene-regulation studies

More Information

Parent CAS No. 3385-03-3
Chemical Name (4aR,4bS,5S,6aS,8R,9S,10aS,12S)-12-Fluoro-5-hydroxy-6b-(2-hydroxy-acetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,
6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one
MFCD MFCD00133324
Short Description Corticosteroid

References

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