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JMJD6 inhibitor WL12
Axon 3180
CAS:
899548-78-8
Purity:
99%
- Soluble in DMSO
- MF: C16H11N3O2
- MW: 277.28
Description
JMJD6 inhibitor WL12 is a first-in-class JMJD6 inhibitor with an IC50 value of 0.22 μM. JMJD6 inhibitor WL12 was shown to be able to suppress JMJD6-dependent cancer cell proliferation including cervical and liver cancer cells. Specifically, the IC50 values for JMJD6 inhibitor WL12 in HeLa and SMCC7721 cells were 2.44 and 10.18 μM, respectively.
More Information
| Parent CAS No. | 899548-78-8 |
|---|---|
| Chemical Name | 3-(1H-Imidazo[4,5-c]pyridin-2-yl)-6-methyl-2H-chromen-2-one |
| SMILES | C12N=C(C3=CC4C=C(C)C=CC=4OC3=O)NC1=CC=NC=2 |
| MFCD | N.A. |
| InChi | InChI=1S/C16H11N3O2/c1-9-2-3-14-10(6-9)7-11(16(20)21-14)15-18-12-4-5-17-8-13(12)19-15/h2-8H,1H3,(H,18,19) |
| InChiKey | AFTXOIIKGOXDOT-UHFFFAOYSA-N |
| CID | 22424483 |
| Short Description | JMJD6 inhibitor |
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