JMJD6 inhibitor WL12 is a first-in-class JMJD6 inhibitor with an IC50 value of 0.22 μM. JMJD6 inhibitor WL12 was shown to be able to suppress JMJD6-dependent cancer cell proliferation including cervical and liver cancer cells. Specifically, the IC50 values for JMJD6 inhibitor WL12 in HeLa and SMCC7721 cells were 2.44 and 10.18 μM, respectively.

KEYWORDS: JMJD6 inhibitor WL12 | supplier | JMJD6 inhibitor | JMJD6 inhibitor WL 12 | JMJD6 inhibitor WL-12 | CAS [899548-78-8] | Histone | Histone demethylase | Inhibitor | Enzymes | Arginine demethylase