Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3164

CAS [75706-12-6]

MF C12H9F3N2O2
MW 270.21

  • Purity: 99%
  • Soluble in DMSO



Leflunomide is a selective inhibitor of de novo pyrimidine synthesis. The active metabolite of Leflunomide, A77 1726, at low, therapeutically applicable doses, reversibly inhibits dihydroorotate dehydrogenase (DHODH), the rate limiting step in the de novo synthesis of pyrimidines. Leflunomide is a disease modifying antirheumatic drug (DMARD).

KEYWORDS: Leflunomide | supplier | DHODH inhibitor | HWA486 | HWA-486 | CAS [75706-12-6] | Dihydroorotate | DHODH | Inhibitor | Enzymes | Rheumatoid arthritis | DMARD

Size Unit Price Stock
50 mg €60.00 In Stock
250 mg €160.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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