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Ambroxol hydrochloride
- Parent CAS: 18683-91-5
- Soluble in water and DMSO
- MF: C13H18Br2N2O.HCl
- MW: 414.56
Description
Ambroxol hydrochloride is an expectorant and mucokinetic compound. Ambroxol hydrochloride is shown to exert several activities: i) secretolytic activity ii) anti-inflammatory and antioxidant activity; and iii) a local anaesthetic effect through sodium channel blocking at the level of the cell membrane.
More Information
| Parent CAS No. | 18683-91-5 |
|---|---|
| Chemical Name | trans-4-(2-Amino-3,5-dibromobenzylamino)cyclohexanol hydrochloride |
| MFCD | MFCD00078932 |
| Short Description | Expectorant |
References
- A Gillissen et al. Characterization of N-acetylcysteine and ambroxol in anti-oxidant therapy. Respir Med. 1998;92(4):609‐623.
- T Weiser et al. Inhibition of tetrodotoxin (TTX)-resistant and TTX-sensitive neuronal Na(+) channels by the secretolytic ambroxol. Mol Pharmacol. 2002;62(3):433‐438.
- M Malerba et al. Ambroxol in the 21st century: pharmacological and clinical update. Expert Opin Drug Metab Toxicol. 2008;4(8):1119-1129.
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