Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3155

CAS [2471982-20-2]

MW 569.21

  • Purity: 98%
  • Soluble in DMSO



CU-115 is a selective TLR8 inhibitor (IC50 value of 1.04 μM). Biological evaluation of CU-115 using human monocyte THP-1, RAW264.7, and Hek 293-Blue TLR cells confirmed that CU-115 is active for inhibiting ssRNA-sensing pathways at low concentrations and does not inhibit other non-endosomal TLR and cytosolic NA-sensing pathways (<5 μ M).

KEYWORDS: CU-115 | supplier | TLR8 inhibitor | CU115 | CU 115 | CAS [2471982-20-2] | DNA-RNA | TLR8 | Inhibitor | Receptors | Autoimmunity

Size Unit Price Stock
10 mg €120.00 In Stock
50 mg €420.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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