Based on 7 reference(s) in Google Scholar 8 10 7

Axon 3057

CAS [346692-04-4]

MW 307.38

  • Purity: 99%
  • Soluble in DMSO



DC260126 is a GPR40 antagonist with an IC50 value of 6.58 μM. DC260126 improves insulin tolerance but not glucose tolerance in obese Zucker rats. Although DC260126 could not provide benefit for improving hyperglycemia, it could protect against pancreatic b-cells dysfunction through reducing overload of b-cells, and it increases insulin sensitivity possibly via alleviation of hyperinsulinemia in db/db mice.

KEYWORDS: DC260126 | GPR40 antagonist | DC 260126 | DC-260126 | CAS [346692-04-4] | FFA | GPR40 | Antagonist | Receptors | Insulin | Glucose | Zucker | Hyperglycemia

Size Unit Price Stock
10 mg €65.00 In Stock
50 mg €165.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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