PLX5622

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3054

CAS [1303420-67-8]

MF C21H19F2N5O
MW 395.41

  • Purity: 98%
  • Soluble in DMSO

PLX5622

Description

PLX5622 is potent, specific, orally bioavailable, and brain-penetrant CSF1R inhibitor with an IC50 value of 0.016 μM. PLX5622 allowed for extended and specific microglial elimination, preceding and during Alzheimer’s disease (AD) pathology development.

KEYWORDS: PLX5622 | supplier | CSF1R inhibitor | PLX 5622 | PLX-5622 | CAS [1303420-67-8] | Interleukin | CSF1R | Inhibitor | Receptors | Alzheimer’s disease | AD

Potent, specific, orally bioavailable and brain-penetrant inhibitor of CSF1R

Chemical name

6-Fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2-amine

Parent CAS No.

[1303420-67-8]

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Size Unit Price Stock
5 mg €95.00 In Stock
25 mg €325.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €140.00 In Stock
2 x 25 mg €500.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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