Bulk Inquiry
PLX5622
Axon 3054
CAS:
1303420-67-8
Purity:
98%
- Soluble in DMSO
- MF: C21H19F2N5O
- MW: 395.41
Description
PLX5622 is potent, specific, orally bioavailable, and brain-penetrant CSF1R inhibitor with an IC50 value of 0.016 μM. PLX5622 allowed for extended and specific microglial elimination, preceding and during Alzheimer’s disease (AD) pathology development.
More Information
| Parent CAS No. | 1303420-67-8 |
|---|---|
| Chemical Name | 6-Fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2-amine |
| SMILES | C1(C)C=C2C(CC3C=CC(NCC4C=C(F)C=NC=4OC)=NC=3F)=CNC2=NC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C21H19F2N5O/c1-12-5-17-14(9-26-20(17)25-8-12)6-13-3-4-18(28-19(13)23)24-10-15-7-16(22)11-27-21(15)29-2/h3-5,7-9,11H,6,10H2,1-2H3,(H,24,28)(H,25,26) |
| InChiKey | NSMOZFXKTHCPTQ-UHFFFAOYSA-N |
| CID | 52936034 |
| Short Description | CSF1R inhibitor |
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 2501 | Pexidartinib |
From $66.00 |
| 2571 | GW 2580 |
From $82.50 |
| 3428 | CSF1R inhibitor compound 22 |
From $143.00 |
| 4084 | Sotuletinib |
From $132.00 |
| 4237 | IL-4-inhibitor-1 |
From $121.00 |
Other Categories
Get a Quote for
Loading...
Are you sure you would like to remove this item from the shopping cart?
This item is a part of the approved quote. Removing it will remove all quote items from the cart.