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Axon 3054
CAS [1303420-67-8]
MF C21H19F2N5OMW 395.41
PLX5622 is potent, specific, orally bioavailable, and brain-penetrant CSF1R inhibitor with an IC50 value of 0.016 μM. PLX5622 allowed for extended and specific microglial elimination, preceding and during Alzheimer’s disease (AD) pathology development.
KEYWORDS: PLX5622 | supplier | CSF1R inhibitor | PLX 5622 | PLX-5622 | CAS [1303420-67-8] | Interleukin | CSF1R | Inhibitor | Receptors | Alzheimer’s disease | AD
6-Fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2-amine
[1303420-67-8]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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