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CSF1R inhibitor compound 22
Axon 3428
CAS:
2095849-04-8
Purity:
99%
- Soluble in DMSO
- MF: C25H20F3N5O2
- MW: 479.45
Description
CSF1R inhibitor compound 22 is a potent, cellular active and orally bioavailable CSF1R inhibitor with an IC50 value of 0.9 nM.
More Information
| Parent CAS No. | 2095849-04-8 |
|---|---|
| Chemical Name | 5-(1-Methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide |
| SMILES | N1C=C(C(=O)NC2C(C)=CC=C(NC(=O)C3C=C(C(F)(F)F)C=CC=3)C=2)C=C(C2=CN(C)N=C2)C=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C25H20F3N5O2/c1-15-6-7-21(31-23(34)16-4-3-5-20(9-16)25(26,27)28)10-22(15)32-24(35)18-8-17(11-29-12-18)19-13-30-33(2)14-19/h3-14H,1-2H3,(H,31,34)(H,32,35) |
| InChiKey | BMEXIUCHJUGPRB-UHFFFAOYSA-N |
| CID | 137333440 |
| Short Description | CSF1R inhibitor |
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