Fatostatin hydrobromide - Fatostatin A hydrobromide | 125B11 hydrobromide

Based on 37 reference(s) in Google Scholar 8 10 37

Axon 2975

CAS [298197-04-3]

MF C18H18N2S.HBr
MW 375.33

  • Purity: 99%
  • Soluble in DMSO
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Fatostatin hydrobromide

Description

Fatostatin hydrobromide is a specific inhibitor of SREBP cleavage-activating protein (SCAP), which is required for SREBP activation. Fatostatin hydrobromide possesses antitumor properties including the inhibition of cancer cell proliferation, invasion, and migration, and it arrests cancer cells in G2/M phase. Fatostatin hydrobromide also inhibits tubulin polymerization, which perturbs mitotic spindle assembly and leads to mitotic catastrophe. Fatostatin hydrobromide has anticancer properties in cell culture and in vivo mouse models of prostate and brain cancers.

KEYWORDS: Fatostatin hydrobromide | supplier | SCAP inhibitor | Fatostatin A hydrobromide | 125B11 hydrobromide | CAS [298197-04-3] | [125256-00-0] | DNA-RNA | SREBP | Inhibitor | Transcription Factors

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10 mg €90.00 In Stock
50 mg €330.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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