Bulk Inquiry
GSK626616
Axon 2970
CAS:
1025821-33-3
Purity:
99%
- Soluble in DMSO
- MF: C18H10Cl2N4OS
- MW: 401.27
Description
GSK626616 is a potent, orally bioavailable inhibitor of DYRK3 with an IC50 value of 0.7 nM. GSK626616 inhibits other members of the DYRK family, e.g., DYRK1A and DYRK2, with similar potency and with an approximate 20-fold selectivity versus the next most potently inhibited kinase, casein kinase 2.
More Information
| Parent CAS No. | 1025821-33-3 |
|---|---|
| Chemical Name | (5Z)-2-(2,6-dichlorophenylimino)-5-(quinoxalin-6-ylmethylene)thiazolidin-4-one |
| SMILES | C1(/C=C2SC(NC3C(Cl)=CC=CC=3Cl)=NC2=O)C=C2N=CC=NC2=CC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C18H10Cl2N4OS/c19-11-2-1-3-12(20)16(11)23-18-24-17(25)15(26-18)9-10-4-5-13-14(8-10)22-7-6-21-13/h1-9H,(H,23,24,25)/b15-9- |
| InChiKey | RJPNRXFBYZVRIB-DHDCSXOGSA-N |
| CID | 135416229 |
| Short Description | DYRK3 inhibitor |
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 2202 | CK2 inhibitor 10 |
From $115.50 |
| 3538 | INDY |
From $121.00 |
| 3540 | ProINDY |
From $121.00 |
| 4056 | DYRK1A inhibitor compound 11 |
From $165.00 |
Other Categories
Get a Quote for
Loading...
Are you sure you would like to remove this item from the shopping cart?
This item is a part of the approved quote. Removing it will remove all quote items from the cart.