BACE-2 Inhibitor - BACE2 Inhibitor 3l

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 2957

CAS [1676107-08-6]

MF C36H38F3N3O3
MW 617.70

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO

BACE-2 Inhibitor

Description

Potent and highly selective human β-secretase 2 (BACE-2) inhibitor with a Ki value of 1.6 nM and >500-fold selectivity over BACE-1.

AK Ghosh et al. Highly Selective and Potent Human ß-Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X-ray Structure and Structure-Activity Relationship Studies. ChemMedChem. 2019 Mar 5;14(5):545-560.

Potent and highly selective BACE 2 inhibitor

Chemical name

N1-((2S,3R)-3-Hydroxy-1-phenyl-4-(3-(trifluoromethyl)benzylamino)butan-2-yl)-N3,5-dimethyl-N3-((R)-1-phenylethyl)isophthalamide

Parent CAS No.

[1676107-08-6]

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5 mg	€140.00	In Stock
25 mg	€520.00	In Stock

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BACE-2 Inhibitor - BACE2 Inhibitor 3l

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BACE-2 Inhibitor - BACE2 Inhibitor 3l

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