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CE3F4
Axon 2929
CAS:
143703-25-7
Purity:
98%
- Soluble in DMSO
- MF: C11H10Br2FNO
- MW: 351.01
Description
CE3F4 is an inhibitor of EPAC1 with an IC50 value of 23 µM. CE3F4 blocked EPAC1 guanine nucleotide exchange activity toward its effector Rap1 both in cell-free systems and in intact cells. The more active enantiomer, (R)-CE3F4 is available as Axon 2830.
More Information
| Parent CAS No. | 143703-25-7 |
|---|---|
| Chemical Name | 5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydroquinoline-1(2H)-carbaldehyde |
| SMILES | C1(F)C(Br)=C2CCC(C)N(C=O)C2=CC=1Br |
| MFCD | MFCD30182244 |
| InChi | InChI=1S/C11H10Br2FNO/c1-6-2-3-7-9(15(6)5-16)4-8(12)11(14)10(7)13/h4-6H,2-3H2,1H3 |
| InChiKey | ZZLQPWXVZCPUGC-UHFFFAOYSA-N |
| CID | 21781066 |
| Short Description | EPAC1 inhibitor |
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