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HJC0350

Axon 2730
CAS:  885434-70-8
Purity:  99%
  • Soluble in DMSO
  • MF:  C15H19NO2S
  • MW:  277.38

Description

HJC0350 is a highly potent and selective EPAC2 antagonist (IC50 value of 0.3 μM for competing with 8-NBD-cAMP binding of EPAC2). Moreover, HJC0350 is about 133-fold more potent than cAMP. Valuable pharmacological tool to explore physiological and pathological processes related to signaling pathways that are regulated by EPAC proteins.

More Information

Parent CAS No. 885434-70-8
Chemical Name 1-(Mesitylsulfonyl)-2,4-dimethyl-1H-pyrrole
SMILES C1(S(N2C(C)=CC(C)=C2)(=O)=O)C(C)=CC(C)=CC=1C
MFCD N.A.
InChi InChI=1S/C15H19NO2S/c1-10-6-12(3)15(13(4)7-10)19(17,18)16-9-11(2)8-14(16)5/h6-9H,1-5H3
InChiKey AFZWZVLPIMHLSE-UHFFFAOYSA-N
CID 22200891
Short Description EPAC2 antagonist

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