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HJC0350
Axon 2730
CAS:
885434-70-8
Purity:
99%
- Soluble in DMSO
- MF: C15H19NO2S
- MW: 277.38
Description
HJC0350 is a highly potent and selective EPAC2 antagonist (IC50 value of 0.3 μM for competing with 8-NBD-cAMP binding of EPAC2). Moreover, HJC0350 is about 133-fold more potent than cAMP. Valuable pharmacological tool to explore physiological and pathological processes related to signaling pathways that are regulated by EPAC proteins.
More Information
| Parent CAS No. | 885434-70-8 |
|---|---|
| Chemical Name | 1-(Mesitylsulfonyl)-2,4-dimethyl-1H-pyrrole |
| SMILES | C1(S(N2C(C)=CC(C)=C2)(=O)=O)C(C)=CC(C)=CC=1C |
| MFCD | N.A. |
| InChi | InChI=1S/C15H19NO2S/c1-10-6-12(3)15(13(4)7-10)19(17,18)16-9-11(2)8-14(16)5/h6-9H,1-5H3 |
| InChiKey | AFZWZVLPIMHLSE-UHFFFAOYSA-N |
| CID | 22200891 |
| Short Description | EPAC2 antagonist |
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