Bulk Inquiry
Y 29794 tosylate
Axon 2911
- Parent CAS: 129184-48-1
Purity:
99%
- Soluble in DMSO
- MF: C23H34N2OS2.C7H8O3S
- MW: 590.86
Description
Y 29794 tosylate is an orally active, potent and specific prolyl endopeptidase (PPCE) inhibitor that is easily penetrable into the brain. Y-29794 tosylate selectively and competitively inhibited rat brain PPCE in a reversible manner with a Ki value of 0.95 nM. Moreover, Y 29794 tosylate exhibited potent inhibitory activity with an IC50 value of 3.0 nM for both brain crude extract and partially purified enzyme fraction.
More Information
| Parent CAS No. | 129184-48-1 |
|---|---|
| Chemical Name | (2-(8-(Dimethylamino)octylthio)-6-isopropylpyridin-3-yl)(thiophen-2-yl)methanone tosylate |
| SMILES | C1C=C(C(=O)C2=CC=CS2)C(SCCCCCCCCN(C)C)=NC=1C(C)C.C1(C)C=CC(S(=O)(=O)O)=CC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C23H34N2OS2.C7H8O3S/c1-18(2)20-14-13-19(22(26)21-12-11-17-27-21)23(24-20)28-16-10-8-6-5-7-9-15-25(3)4;1-6-2-4-7(5-3-6)11(8,9)10/h11-14,17-18H,5-10,15-16H2,1-4H3;2-5H,1H3,(H,8,9,10) |
| InChiKey | CSLUSHFIPGHVIY-UHFFFAOYSA-N |
| CID | 9851449 |
| Short Description | PPCE inhibitor |
