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PKG drug G1 sodium salt
- Parent CAS: 374703-78-3
- Soluble in water and DMSO
- MF: C13H10N3NaOS
- MW: 279.29
Description
PKG drug G1 sodium salt has been shown to induce the oxidative activation of protein kinase G Iα, which in vivo results in dilation of blood vessel and blood pressure lowering; an antihypertensive. The parent molecule, PKG drug G1 (Axon 2232), is also available.
* Developed and sold in collaboration with KCL (King's College of London).
More Information
| Parent CAS No. | 374703-78-3 |
|---|---|
| Chemical Name | Sodium 2-methyl-3-((5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)indol-1-ide |
| SMILES | C1=CC2C(/C=C3/C(=O)[N-]C(=S)N/3)=C(C)NC=2C=C1.[Na+] |
| MFCD | N.A. |
| InChi | InChI=1S/C13H11N3OS.Na/c1-7-9(6-11-12(17)16-13(18)15-11)8-4-2-3-5-10(8)14-7;/h2-6H,1H3,(H3,14,15,16,17,18);/q;+1/p-1 |
| InChiKey | KUDYLQWRRNWNJB-UHFFFAOYSA-M |
| CID | 134824565 |
| Short Description | PKG Iα inducer |
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|---|---|---|
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