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PKG drug G1
Axon 2232
CAS:
374703-78-3
Purity:
99%
- Soluble in DMSO
- MF: C13H11N3OS
- MW: 257.31
Description
PKG drug G1 has been shown to induce the oxidative activation of protein kinase G Iα, which in vivo results in dilation of blood vessel and blood pressure lowering; an antihypertensive. The water soluble salt form, PKG drug G1 sodium salt (Axon 2905), is also available.
* Developed and sold in collaboration with KCL (King's College of London).
More Information
| Parent CAS No. | 374703-78-3 |
|---|---|
| Chemical Name | 5-((2-Methyl-1H-indol-3-yl)methylene)-2-thioxoimidazolidin-4-one |
| SMILES | C1(=S)N/C(=CC2C3=C(NC=2C)C=CC=C3)/C(=O)N1 |
| MFCD | N.A. |
| InChi | InChI=1S/C13H11N3OS/c1-7-9(6-11-12(17)16-13(18)15-11)8-4-2-3-5-10(8)14-7/h2-6,14H,1H3,(H2,15,16,17,18)/b11-6- |
| InChiKey | SNLLEQAPNVMOOT-WDZFZDKYSA-N |
| CID | 135402990 |
| Short Description | PKG Iα inducer |
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