Nolatrexed dihydrochloride - AG 337 | Thymitaq

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2853

CAS [152946-68-4]

MF C14H14Cl2N4OS
MW 357.26

  • Purity: 98%
  • Soluble in DMSO and water

Nolatrexed dihydrochloride

Description

Nolatrexed dihydrochloride is a water soluble, lipophilic inhibitor of thymidylate synthase (Ki value of 11 nM). Nolatrexed dihydrochloride displayed non-competitive inhibition kinetics and was shown to inhibit cell growth in a panel of cell lines of murine and human origin (IC50 values between 0.39 and 6.6 µM).

KEYWORDS: Nolatrexed dihydrochloride | supplier | Thymidylate synthase inhibitor | AG 337 | Thymitaq | AG337 | AG-337 | CAS [152946-68-4] | [147149-76-6] | Deoxyuridine monophosphate (dUMP) | TYMS | Inhibitor | Enzymes

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10 mg €120.00 In Stock
50 mg €360.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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