LB-100 - LB-1

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2820

CAS [1632032-53-1]

MF C13H20N2O4
MW 268.31

  • Purity: 99%
  • Soluble in water and DMSO



LB-100 is a specific competitive inhibitor of PP2A. In a mouse xenograft model of human pancreatic cancer, LB-100 produced significant radiosensitization with minimal weight loss. Furthermore, LB-100 decreased cell viability through caspase activation and G2/M cell-cycle arrest. LB100 enhanced daunorubicin cytotoxicity resulting in decreased xenograft volumes and improved overall survival.

KEYWORDS: LB-100 | supplier | PP2A inhibitor | LB-1 | LB100 | LB 100 | LB1 | LB 1 | CAS [1632032-53-1] | Non Selective (Tyrosine Specific Phosphomonoesters) | PP2A | Inhibitor | Enzymes

Size Unit Price Stock
10 mg €110.00 In Stock
50 mg €400.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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