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Axon 2721
CAS [924473-59-6]
MF C19H14F3N3O3MW 389.33
T56-LIMKi is an inhibitor of LIMK2. T56-LIMKi efficiently inhibited the growth of NF1-/- MEF, ST88-14, U87, and Panc-1 cells with IC50 values of 30 μM, 18 μM, 7 μM, and 35 μM, respectively. Moreover, T56-LIMKi reduced tumor size and p-cofilin levels in the Panc-1 tumors in vivo. Potential drug for pancreatic cancer, glioma and schwannoma cells.
KEYWORDS: T56-LIMKi | supplier | LIMK2 inhibitor | T5601640 | T56 LIMKi | T56LIMKi | T 5601640 | T-5601640 | CAS [924473-59-6] | Non Selective (ADF-cofilin) | LIMK2 | Inhibitor | Enzymes | LIM | LIM kinase | cofilin | ADF | Panc-1
3-Methyl-N-(3-(3-(trifluoromethyl)phenylcarbamoyl)phenyl)isoxazole-5-carboxamide
[924473-59-6]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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