JavaScript seems to be disabled in your browser. You must have JavaScript enabled in your browser to utilize the functionality of this website.
There are no items in your shopping cart
Featured Products
Axon 2661
CAS [1845753-81-2]
MF C24H23NO3MW 373.44
AZD2716 is a novel, potent sPLA2 inhibitor (IC50 values of 10, 40, and 400 nM for sPLA2-IIa, -V, and -X, respectively) with excellent preclinical pharmacokinetic properties across species, clear in vivo efficacy, and minimized safety risk. When incubated with HepG2 cells, AZD2716 effectively inhibited sPLA2 activity (IC50 value of <14 nM) and suppressed production of sPLA2-IIa (IC50 value of 176 nM). AZD2716 also demonstrated significant sPLA2 activity inhibition (IC50 value of 56 nM) in atherosclerotic plaque homogenates.
KEYWORDS: AZD2716 | supplier | sPLA2 inhibitor | AZD 2716 | AZD-2716 | CAS [1845753-81-2] | Phospholipids | PLA2 | Inhibitor | Enzymes | Coronary Artery Disease
(R)-3-(5'-Benzyl-2'-carbamoylbiphenyl-3-yl)-2-methylpropanoic acid
[1845753-81-2]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
* Required Fields