Based on 2 reference(s) in Google Scholar 9 10 2

Axon 2623

CAS [1916571-90-8]

MF C20H23F3N4S
MW 408.48

  • Purity: 98%
  • Soluble in 0.1N HCl (aq) and DMSO



Non-competitive PHGDH inhibitor (IC50 value 2.5 µM) that reduces the production of glucose-derived serine in cells and suppresses the growth of PHGDH-dependent cancer cells in culture and in orthotopic xenograft tumors.

KEYWORDS: NCT-503 | supplier | PHGDH inhibitor | NCT503 | NCT 503 | CAS [1916571-90-8] | 3-phosphoglycerate | 3-PG | serine | cancer | NSCLC | phosphoglycerate dehydrogenase

Size Unit Price Stock
10 mg €105.00 In Stock
50 mg €365.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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