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Featured Products
Axon 2584
CAS [312756-74-4]
MF C20H16Br2N2O3SMW 524.23
Enhancer of CRISPR-based genome editing and homology-directed repair (HDR; RAD51). RS-1 can enhance filament stability, and stimulated hRAD51-mediated homologous strand assimilation (D-loop) activity by at least 5- to 11-fold. RS-1 acts as an allosteric regulator that locks hRAD51 in an active conformation and does so without influencing the active site for ATP hydrolysis. Treatment with RS-1 promoted significant antitumor responses in a mouse model.
KEYWORDS: RS-1 | supplier | RAD51 stimulator | RAD51-Stimulatory Compound-1 | RS1 | CAS [312756-74-4] | DNA-RNA | RAD51 | Stimulator | CRISPR | genome editing | homology-directed repair | HDR | filaments | Cas9
3-(N-benzylsulfamoyl)-4-bromo-N-(4-bromophenyl)benzamide
[312756-74-4]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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