C-DIM12 - DIM-C-pPhCl

Based on 11 reference(s) in Google Scholar 10 10 11

Axon 2575

CAS [178946-89-9]

MF C23H17ClN2
MW 356.85

  • Purity: 99%
  • Soluble in DMSO



Potent and specific Nurr1 activator that stimulates Nurr1 mediated apoptosis axis in bladder cancer cells and tumors and inhibits NF-κB–dependent gene expression in glial cells by stabilizing nuclear corepressor proteins, which reduces binding of p65 to inflammatory gene promoters. C-DIM12 protects against loss of dopamine neurons in the substantia nigra as well as dopamine terminals in the striatum in MPTP-induced mouse models for Parkinson's disease.

KEYWORDS: C-DIM12 | supplier | Nurr1 activator | DIM-C-pPhCl | CDIM12 | C-DIM 12 | CAS [178946-89-9] | Intracellular Transcription Factors | NURR | Activator | Nuclear Receptors | NR4A2 | inflammation | CNS | dopaminergic | neurons | NF-κB | ganglia | Parkinson's

Size Unit Price Stock
10 mg €85.00 In Stock
50 mg €255.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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