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Axon 2561
CAS [1609564-75-1]
MF C30H32N4O5SMW 560.66
Highly potent FXR antagonist with a promising in vitro profile (IC50 values 7.5 nM and 468.5 nM in FXR binding assay and cell-based FXR antagonistic assay, respectively). DY 268 shows no FXR agonistic activity nor cytotoxicity, making it an excellent chemical tool to elucidate the biological function of FXR.
KEYWORDS: DY 268 | supplier | FXR antagonist | DY268 | CAS [1609564-75-1] | Chenodeoxycholic acid | FXR | Antagonist | Nuclear | Farnesoid X Receptor | cholesterol | metabolism
1-(3-methoxybenzyl)-N-(4-methyl-3-(morpholinosulfonyl)phenyl)-3-p-tolyl-1H-pyrazole-4-carboxamide
[1609564-75-1]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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