Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2479

CAS [1643659-63-5]

MF C14H22N2O3
MW 266.34

  • Purity: 100%
  • Soluble in water and DMSO



Orally active iron chelator with high affinity and selectivity for iron(III) (relative metal complex stability constants of pFe(III)= 20.3; pCu(II)= 9.8; pZn(II)= 6.2) and a suit-able partition coefficient to permeate membranes. CM1 is able to penetrate hepatocytes and relatively non toxic. Potential therapeutic for patients suffering from thalassaemia related iron overload Moreover, CM1 shows an inhibitory effect on the growth of Plasmodium falciparum (malaria parrasite; IC50 value 35 µM).

KEYWORDS: CM1 | supplier | Iron chelator | CAS [1643659-63-5] | Iron (III) | FE(III) | Chelator | thalassaemia | hepatocytes | malaria | parasite | Plasmodium

Size Unit Price Stock
10 mg €95.00 In Stock
50 mg €345.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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