Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2411

CAS [890190-22-4]

MF C21H25N3O4
MW 383.44

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO



Inhibitor of WD40 repeat protein 5 (WDR5) and associated activity of H3K4 HMTase MLL (Kd value 0.45 µM for WDR5 binding, and IC50 value of 39 μM for inhibition of methyltransferase activity of MLL complex). Potential therapeutic for treatment of MLL-rearranged leukemias or other cancers.
Size Unit Price Stock
10 mg €90.00 In Stock
50 mg €350.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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