UNC 2250

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2346

CAS [1493694-70-4]

MF C24H36N6O2
MW 440.58

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

UNC 2250

Description

Potent Mer kinase inhibitor (in vitro IC50 values 1.7 nM, 270 nM, and 100 nM for Mer, Axl, and Tyro3 RTKs, respectively) with promising selectivity and PK properties. UNC 2250 efficiently inhibited both steady state and ligand-stimulated phosphorylation of Mer, and confirmed functional antitumor activity by exhibiting potential to reduced colony-forming in both rhabdoid tumor cells and NSCLC cells.

KEYWORDS: UNC 2250 | supplier | Mer Inhibitor | UNC2250 | CAS [1493694-70-4] | Gas6 | Mer | TAM | RTK | Axl | Tyro3 | antitumor | rhabdoid | NSCLC | lung cancer

Order
Size Unit Price Stock
5 mg €80.00 In Stock
25 mg €280.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €120.00 In Stock
2 x 25 mg €420.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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