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AZ-GHS-22

Axon 2340
CAS:  1143020-91-0
Purity:  98%
  • Soluble in 0.1N HCl(aq) and DMSO
  • MF:  C27H33ClN6O5S2
  • MW:  621.17

Description

Orally available high affinity Ghrelin receptor (GHS-R1a) inverse agonist (IC50 0.77 nM) with very low CNS exposure.

More Information

Parent CAS No. 1143020-91-0
Chemical Name 2-chloro-N-(6-(3-(4-methylpiperazin-1-yl)propylsulfonyl)benzo[d]thiazol-2-ylcarbamoyl)-5-morpholinobenzamide
SMILES C(C1=CC(N2CCOCC2)=CC=C1Cl)(NC(NC1=NC2=CC=C(S(CCCN3CCN(C)CC3)(=O)=O)C=C2S1)=O)=O
MFCD N.A.
InChi InChI=1S/C27H33ClN6O5S2/c1-32-8-10-33(11-9-32)7-2-16-41(37,38)20-4-6-23-24(18-20)40-27(29-23)31-26(36)30-25(35)21-17-19(3-5-22(21)28)34-12-14-39-15-13-34/h3-6,17-18H,2,7-16H2,1H3,(H2,29,30,31,35,36)
InChiKey XWFQFKFKWKWIEW-UHFFFAOYSA-N
CID 57422817
Short Description GHS-R1a inverse agonist

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