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CpdD hydrochloride
- GhrR antagonist CpdD
Axon 2147
- Parent CAS: 916984-47-9
- Optical Purity: Optically pure
- Soluble in water and DMSO
- MF: C25H33BrN4O3S.HCl
- MW: 585.98
Description
CpdD hydrochloride is a selective antagonist of the ghrelin receptor GHSR-1a (GhrR). It is used to block ghrelin-mediated receptor signaling in metabolic, endocrine and appetite-regulation studies.
Ghrelin receptor signaling regulates growth hormone release, feeding behavior, energy homeostasis and gastrointestinal/endocrine function. CpdD is pharmacologically relevant for separating GHSR-1a-dependent effects from broader metabolic signaling networks.
Key Features
- Selective ghrelin receptor antagonist
- Targets GHSR-1a-mediated signaling
- Blocks ghrelin pathway activation
- Useful endocrine and metabolic receptor tool
Applications
- Ghrelin receptor pharmacology
- Appetite and energy-balance studies
- Endocrine signaling assays
- Metabolic disease model research
More Information
| Parent CAS No. | 916984-47-9 |
|---|---|
| Chemical Name | (R)-N-(1-(3-(4-bromobenzyl)-1,2,4-oxadiazol-5-yl)-3-phenylpropyl)-3-(diethylamino)propane-1-sulfonamide hydrochloride |
| SMILES | C(S(N[C@@H](C1ON=C(CC2=CC=C(Br)C=C2)N=1)CCC1=CC=CC=C1)(=O)=O)CCN(CC)CC.Cl |&1:3,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C25H33BrN4O3S.ClH/c1-3-30(4-2)17-8-18-34(31,32)29-23(16-13-20-9-6-5-7-10-20)25-27-24(28-33-25)19-21-11-14-22(26)15-12-21;/h5-7,9-12,14-15,23,29H,3-4,8,13,16-19H2,1-2H3;1H/t23-;/m1./s1 |
| InChiKey | WILYCIHDBDOFAQ-GNAFDRTKSA-N |
| CID | 91826500 |
| Short Description | GhrR antagonist |
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