DDR1-IN-1

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2265

CAS [1449685-96-4]

MF C30H31F3N4O3
MW 552.59

Purity: 98%
Soluble in DMSO

DDR1-IN-1

Description

Potent and selective DDR1 receptor tyrosine kinase (RTK) inhibitor (IC50 values 105 and 413 nM for DDR1 and DDR2 respectively); a useful pharmacological probe for DDR1-dependent signal transduction.

H.G. Kim et al. Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor. A.C.S. Chem. Biol. 2014, 9, 840.

P. Canning et al. Structural mechanisms determining inhibition of the collagen receptor DDR1 by selective and multi-targeted type II kinase inhibitors. J. Mol. Biol. 2014, 426, 2457-2470.

Cell Signaling & Oncology DDR RTK class XVI; EC 2.7.10.1

Selective DDR1 receptor tyrosine kinase (RTK) inhibitor

Chemical name

4-((4-Ethylpiperazin-1-yl)methyl)-N-(4-methyl-3-(2-oxoindolin-5-yloxy)phenyl)-3-(trifluoromethyl)benzamide

Parent CAS No.

[1449685-96-4]

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Size	Unit Price	Stock
5 mg	€95.00	In Stock
25 mg	€335.00	In Stock

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Size	Unit Price	Stock
2 x 5 mg	€140.00	In Stock
2 x 25 mg	€560.00	In Stock

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DDR1-IN-1

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