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BFF 122

Based on 24 reference(s) in Google Scholar 9 10 24

Axon 2237

CAS [1152314-49-2]

MF C17H19FN4O4
MW 362.36

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in 0.1N HCl(aq) and DMSO

BFF 122

Description

Potent and selective inhibitor of kynurenine aminotransferase II (IC50 values ca. 1 μM and >30 μM for KAT II and KAT I respectively). Intrastriatal BFF 122 decreased newly formed KYNA by 66%, without influencing 3-HK or QUIN production in naïve rats.
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5 mg €165.00 In Stock
25 mg €605.00 In Stock
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2 x 5 mg €260.00 In Stock
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Related Products

Axon ID Name Description From price
2118 UPF 648 Potent inhibitor of kynurenine-3-monooxygenase (KMO) €110.00
2139 RO 61-8048 Inhibitor of kynurenine-3-monooxygenase (KMO) €95.00
2215 INCB 024360-analog Potent inhibitor of indoleamine 2,3-dioxygenase-1 (IDO1) €85.00
2924 PF 04859989 hydrochloride Potent, selective, brain-penetrant, irreversible inhibitor of kynurenine aminotransferase II €110.00

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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