LDK 378 - Ceritinib

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2224

CAS [1032900-25-6]

MF C28H36ClN5O3S
MW 558.14

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

LDK 378


Potent, bioavailable, and selective anaplastic lymphoma kinase (ALK) inhibitor (IC50 value 0.2 nM) with >35 fold selectivity over InsR, IGF-1R. LDK 378 induced a dose-dependent tumor growth inhibition and tumor regression in multiple rat xenograft models.
Size Unit Price Stock
5 mg €95.00 In Stock
25 mg €285.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €140.00 In Stock
2 x 25 mg €420.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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