GSK 2578215A

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2181

CAS [1285515-21-0]

MF C24H18FN3O2
MW 399.42

  • Purity: 99%
  • Soluble in DMSO

GSK 2578215A

Description

Potent and exceptionally highly selective Leucine-rich repeat kinase 2 (LRRK2) inhibitor (IC50 values 10.9 and 8.9 nM for wild-type LRRK2 and LRRK2[G2019S] mutant, respectively.) GSK2578215A possesses good blood-brain barrier (BBB) permeability with a high ratio of brain to plasma distribution in mice.
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10 mg €125.00 In Stock
50 mg €450.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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