PX 20350 - FXR agonist Cpd 22

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2152

CAS [1198085-23-2]

MF C28H22Cl2F3N3O4
MW 592.39

  • Purity: 99%
  • Soluble in DMSO

PX 20350


Potent farnesoid X receptor (FXR) agonist with enhanced affinity and efficacy (12 nM and 109% (compared to GW 4064)) in FXR FRET assay and full length FXR direct reporter (DR) assay (6 nM vs 30 nM for GW 4064). Cpd 22 showed a linear dose-dependent reduction in total plasma triglycerides and total plasma cholesterol.
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5 mg €105.00 In Stock
25 mg €365.00 In Stock
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Size Unit Price Stock
2 x 5 mg €160.00 In Stock
2 x 25 mg €560.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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