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Dalcetrapib
- JTT 705
Axon 1962
CAS:
211513-37-0
Purity:
99%
- Soluble in DMSO and EtOH
- MF: C23H35NO2S
- MW: 389.59
Description
Potent cholesterylester transfer protein (CETP) inhibitor
More Information
| Parent CAS No. | 211513-37-0 |
|---|---|
| Chemical Name | S-2-(1-(2-ethylbutyl)cyclohexanecarboxamido)phenyl 2-methylpropanethioate |
| SMILES | C(SC1=CC=CC=C1NC(C1(CC(CC)CC)CCCCC1)=O)(=O)C(C)C |
| MFCD | MFCD06407886 |
| InChi | InChI=1S/C23H35NO2S/c1-5-18(6-2)16-23(14-10-7-11-15-23)22(26)24-19-12-8-9-13-20(19)27-21(25)17(3)4/h8-9,12-13,17-18H,5-7,10-11,14-16H2,1-4H3,(H,24,26) |
| InChiKey | YZQLWPMZQVHJED-UHFFFAOYSA-N |
| CID | 6918540 |
| Short Description | CETP inhibitor |
References
- Z Huang et al. Cholesteryl ester transfer protein inhibitor (JTT-705) and the development of atherosclerosis in rabbits with severe hypercholesterolaemia. Clin Sci (Lond). 2002, 103(6), 587-594.
- T.F. Lüscher et al. Vascular effects and safety of dalcetrapib in patients with or at risk of coronary heart disease: the dal-VESSEL randomized clinical trial. Eur. Heart J. 2012, 33(7), 857-865.
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