P 505-15 - PRT 062607

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1936

CAS [1370261-96-3]

MF C19H23N9O
MW 393.45

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO

P 505-15

Description

Highly specific and potent inhibitor of spleen tyrosine kinase (Syk) (IC50: 1-2 nM)

G Coffey et al. Specific Inhibition of Spleen Tyrosine Kinase Suppresses Leukocyte Immune Function and Inflammation in Animal Models of Rheumatoid Arthritis. J. Pharmacol. Exp. Ther. 2012, 340(2), 350-359.

J Hoellenriegel et al. Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration.

Inhibitor of spleen tyrosine kinase (Syk)

Chemical name

4-(3-(2H-1,2,3-triazol-2-yl)phenylamino)-2-((1R,2S)-2-aminocyclohexylamino)pyrimidine-5-carboxamide

Parent CAS No.

[1370261-96-3]

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Size	Unit Price	Stock
5 mg	€90.00	In Stock
25 mg	€300.00	In Stock

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Size	Unit Price	Stock
2 x 5 mg	€140.00	In Stock
2 x 25 mg	€480.00	In Stock

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Axon ID	Name	Description
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3997	ASN-002	Potent dual inhibitor of SYK and pan-JAK kinases	Inquire
4153	GS-9973	Selective Syk inhibitor	Inquire

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P 505-15 - PRT 062607

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P 505-15 - PRT 062607

Description

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