MK 0822 - Odanacatib

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1771

CAS [603139-19-1]

MF C25H27F4N3O3S
MW 525.56

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO

MK 0822

Description

Potent and selective inhibitor of cathepsin K (CTSK or Cat K)

CL Le Gall et al. Cathepsin K inhibitors as treatment of bone metastasis. Curr. Opin. Support. Palliat. Care. 2008, 2(3), 218.

JY Gauthier et al. The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K. Bioorg. Med. Chem. Lett. 2008, 18(3), 923–928.

EM Lewiecki. Odanacatib, a cathepsin K inhibitor for the treatment of osteoporosis and other skeletal disorders associated with excessive bone remodeling. IDrugs. 2009, 12(12), 799-809.

Inhibitor of cathepsin K

Chemical name

(S)-N-(1-cyanocyclopropyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)pentanamide

Parent CAS No.

[603139-19-1]

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Size	Unit Price	Stock
2 mg	€60.00	In Stock
5 mg	€90.00	In Stock
25 mg	€300.00	In Stock

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2 x 5 mg	€140.00	In Stock

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Related Products

Axon ID	Name	Description	From price
2154	Balicatib	Selective inhibitor of cathepsin K		€50.00
2156	ONO 5334	Potent and orally available inhibitor of cathepsin K		€140.00

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