JavaScript seems to be disabled in your browser.
You must have JavaScript enabled in your browser to utilize the functionality of this website.

Axon Medchem

All

Home
Products
- Shop By Category
- Featured Products
- Shop By Alphabet
  - A
  - B
  - C
  - D
  - E
  - F
  - G
  - H
  - I
  - J
  - K
  - L
  - M
  - N
  - O
  - P
  - Q
  - R
  - S
  - T
  - U
  - V
  - W
  - X
  - Y
  - Z
  - #
Support
- - Customer Support
  - Customer Services
Contact
- About Axon Medchem
- Contact Us

Osanetant - SR 142801

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1533

CAS [160492-56-8]

MF C35H41Cl2N3O2
MW 606.62

Purity: 98%
Optical purity: Optically pure
Soluble in DMSO

Osanetant

Description

Potent non-peptide neurokinin 3 (NK3) receptor antagonist

X Emonds-Alt et al. SR 142801, the first potent non-peptide antagonist of the tachykinin NK3 receptor. Life Sci. 1995, 56(1), PL27-32.

F Kamali. Osanetant Sanofi-Synthélabo. Curr. Opin. Invest. Drugs. 2001, 2(7), 950-956.

L Quartara and M Altamura. Tachykinin receptors antagonists: from research to clinic. Curr. Drug Targets. 2006, 7(8), 975-992.

MA De Souza Silva et al. The tachykinin NK3 receptor antagonist SR142801 blocks the behavioral effects of cocaine in marmoset monkeys. Eur. J. Pharmacol. 2006, 536(3), 269-278.

G Jocham et al. Neurokinin receptor antagonism attenuates cocaine's behavioural activating effects yet potentiates its dopamine-enhancing action in the nucleus accumbens core. Eur. J. Neurosci. 2006, 24(6), 1721-1732.

List of publications using Osanetant (Axon 1533) purchased from Axon Medchem

CNS Pain & Inflammation A9 Tachykinin (NK)

NK3 antagonist

Chemical name

N-(1-{3-[(R)-1-Benzoyl-3-(3,4-dichloro-phenyl)-piperidin-3-yl]-propyl}-4-phenyl-piperidin-4-yl)-N-methyl-acetamide

Parent CAS No.

[160492-56-8]

Order

Size	Unit Price	Stock
5 mg	€160.00	In Stock
25 mg	€660.00	In Stock

Need more? Bulk Inquiry

Related Products

Axon ID	Name	Description	From price
1119	GR 159897	NK2 antagonist		€120.00
1486	Aprepitant	Substance P antagonist (SPA); NK1 inhibitor		€80.00
1618	Orvepitant maleate	NK1 antagonist		€115.00
1901	Casopitant mesylate	NK1 antagonist		€125.00
2499	Netupitant	Selective NK1 antagonist; Prevents chemotherapy-induced nausea and vomiting		€140.00
3138	Lopinavir	HIV-1 protease inhibitor		€80.00
3403	Fezolinetant	Orally bioavailable NK3 antagonist		€140.00

Please wait...