Bulk Inquiry
GR 159897
Axon 1119
CAS:
158848-32-9
- Optical Purity: 98% e.e.
- Soluble in DMSO
- MF: C23H27FN2O2S
- MW: 414.54
Description
Potent and selective non-peptide neurokinin NK2 receptor antagonist
More Information
| Parent CAS No. | 158848-32-9 |
|---|---|
| Chemical Name | 3-[2-(4-(R)-Benzenesulfinylmethyl-4-methoxy-piperidin-1-yl)-ethyl]-5-fluoro-1H-indole |
| SMILES | C1NC2C=CC(F)=CC=2C=1CCN1CCC(OC)(C[S@+](C2C=CC=CC=2)[O-])CC1 |&1:19,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C23H27FN2O2S/c1-28-23(17-29(27)20-5-3-2-4-6-20)10-13-26(14-11-23)12-9-18-16-25-22-8-7-19(24)15-21(18)22/h2-8,15-16,25H,9-14,17H2,1H3/t29-/m1/s1 |
| InChiKey | BANYJBHWTOJQDU-GDLZYMKVSA-N |
| CID | 9953599 |
| Short Description | NK2 antagonist |
References
- DM Walsh et al. The anxiolytic-like activity of GR 159897, a non-peptide NK2 receptor antagonist, in rodent and primate models of anxiety. Psychopharmacol. 1995, 121, 186-191.
- AWJ Cooper et al. GR 159897 and related analogues as highly potent, orally active non-peptide neurokinin NK2 receptor antagonists. Bioorg. Med. Chem. Lett. 1994, 4(16), 1951.
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1486 | Aprepitant |
From $88.00 |
| 1533 | Osanetant |
From $209.00 |
| 1618 | Orvepitant maleate |
From $126.50 |
| 1901 | Casopitant mesylate |
From $137.50 |
| 2499 | Netupitant |
From $154.00 |
Other Categories
Get a Quote for
Loading...
Are you sure you would like to remove this item from the shopping cart?
This item is a part of the approved quote. Removing it will remove all quote items from the cart.