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CGS 12066B
- Parent CAS: 109028-09-3
- Soluble in DMSO
- MF: C17H17F3N4.2C4H4O4
- MW: 566.48
Description
CGS 12066B is a selective serotonin 5-HT1B receptor agonist used to activate 5-HT1B-mediated Gi/o-coupled signaling.
5-HT1B receptors function as presynaptic auto- and heteroreceptors that regulate serotonin release and other neurotransmitter systems. CGS 12066B is useful for studying serotonergic control of neurotransmission, vascular tone and CNS signaling.
Key Features
- Selective 5-HT1B receptor agonist
- Activates Gi/o-coupled serotonergic signaling
- Useful for presynaptic serotonin receptor studies
- Supports CNS and vascular 5-HT1B pharmacology
Applications
- 5-HT1B receptor activation assays
- Serotonergic neurotransmission studies
- Presynaptic receptor function research
- CNS and vascular serotonin pathway models
More Information
| Parent CAS No. | 109028-09-3 |
|---|---|
| Chemical Name | 4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrrolo[1,2-a]quinoxaline dimaleate |
| SMILES | C1(=NC2=C(C=CC(C(F)(F)F)=C2)N2C=CC=C12)N1CCN(C)CC1.C(/C(=O)O)=C/C(=O)O.C(/C(=O)O)=C/C(=O)O |
| MFCD | MFCD00055048 |
| InChi | InChI=1S/C17H17F3N4.2C4H4O4/c1-22-7-9-23(10-8-22)16-15-3-2-6-24(15)14-5-4-12(17(18,19)20)11-13(14)21-16;2*5-3(6)1-2-4(7)8/h2-6,11H,7-10H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1- |
| InChiKey | HTEVMLYDEWVIQE-SPIKMXEPSA-N |
| CID | 9915956 |
| Short Description | 5-HT1B agonist |
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