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Flumethasone

Axon 1169
CAS:  2135-17-3
  • Optical Purity:  Optically pure
  • Soluble in DMSO
  • MF:  C22H28F2O5
  • MW:  410.45

Description

Selective and potent topical glucocorticoid receptor agonist (IC50 value 0.26 nM for human GR). For the treatment of various allergic, inflammatory, and autoimmune disorders.

More Information

Parent CAS No. 2135-17-3
Chemical Name (6S,9R,10S,11S,13S,16R,17R)-6,9-Difluoro-11,17-dihydroxy-17-(2-hydroxy-acetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one
SMILES [C@@]12([H])C[C@@H](C3=CC(C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@]1(C)[C@@]([C@H](C)C[C@@]21[H])(O)C(=O)CO)=O)F |&1:0,3,9,11,13,16,18,19,22,r|
MFCD N.A.
InChi InChI=1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1
InChiKey WXURHACBFYSXBI-GQKYHHCASA-N
CID 16490
Short Description Glucocorticoid agonist

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