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Genipin
Axon 1443
CAS:
6902-77-8
Purity:
99%
- Soluble in DMSO and EtOH
- MF: C11H14O5
- MW: 226.23
Description
Active medication to relieve the symptoms of type 2 diabetes. Genipin stimulates insulin secretion in UCP2-dependent manner (Uncoupling protein 2). Genipin is a protein, collagen, gelatin, and chitosan cross-linker
More Information
| Parent CAS No. | 6902-77-8 |
|---|---|
| Chemical Name | (1R,4aS,7aS)-1-Hydroxy-7-hydroxymethyl-1,4a,5,7a-tetrahydro-cyclopenta[c]pyran-4-carboxylic acid methyl ester |
| MFCD | MFCD00888600 |
| Short Description | Protein cross-linker |
References
- LE Parton et al. Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired by obesity. Nature 2007, 449, 228-233.
- C Zhang et al. Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced B cell dysfunction in isolated pancreatic islets. Cell Metab. 2006, 3, 417-427.
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