Bulk Inquiry
AM 580
- CD336 - NSC 608001 - RO 40-6055
- Soluble in DMSO
- MF: C22H25NO3
- MW: 351.44
Description
AM 580 is a RAR-α agonist with EC50 values of 0.3 nM, 8.6 nM and 13.0 nM for RAR-α, RAR-β and RAR-γ, respectively.
More Information
| Parent CAS No. | 102121-60-8 |
|---|---|
| Chemical Name | 4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carboxamido)benzoic acid |
| SMILES | C1C(C)(C)C2C=C(C(=O)NC3C=CC(C(=O)O)=CC=3)C=CC=2C(C)(C)C1 |
| MFCD | MFCD00673916 |
| InChi | InChI=1S/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-15(7-10-17(18)21)19(24)23-16-8-5-14(6-9-16)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26) |
| InChiKey | SZWKGOZKRMMLAJ-UHFFFAOYSA-N |
| CID | 2126 |
| Short Description | RAR-α agonist |
References
- K Takagi et al. Inhibition of ornithine decarboxylase induction by retinobenzoic acids in relation to their binding affinities to cellular retinoid-binding proteins. J Cancer Res Clin Oncol. 1988;114(3):221-4.
- J Charton et al. Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives. Bioorg Med Chem Lett. 2009 Jan 15;19(2):489-92.
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1173 | BMS 270394 |
From $181.50 |
| 1194 | BMS 189961 |
From $159.50 |
| 1241 | CH 55 |
From $99.00 |
| 1242 | LE 135 |
From $132.00 |
| 2637 | LY 2955303 dihydrochloride |
From $159.50 |
| 2679 | AR7 |
From $99.00 |
| 2902 | QX77 |
From $132.00 |
| 3321 | Retinoic acid |
From $55.00 |
Other Categories
Are you sure you would like to remove this item from the shopping cart?
This item is a part of the approved quote. Removing it will remove all quote items from the cart.