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TAS2940

Axon 4272
CAS:  2451398-65-3
  • Optical Purity:  98% e.e.
  • Soluble in DMSO
  • MF:  C28H30N6O2
  • MW:  482.58

Description

TAS2940 is an orally active, brain-penetrable, and irreversible pan-ERBB inhibitor. TAS2940 has promising therapeutic effects against cancers harboring HER2/EGFR mutations, especially metastatic and primary brain tumors.

More Information

Parent CAS No. 2451398-65-3
Chemical Name 7-((3R,5S)-1-Acryloyl-5-methylpyrrolidin-3-yl)-4-amino-6-(cyclopropylethynyl)-N-((R)-1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide
extra_info Sold in collaboration with Chemietek
SMILES N1C(N)=C2C(C(N[C@H](C)C3C=CC=CC=3)=O)=C(C#CC3CC3)N([C@H]3CN(C(=O)C=C)[C@@H](C)C3)C2=NC=1 |&1:7,23,30,r|
MFCD N.A.
InChi N.A.
InChiKey N.A.
CID N.A.
Short Description pan-ERBB inhibitor

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