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AZD0156
Axon 4140
CAS:
1821428-35-6
Purity:
99%
- Soluble in DMSO
- MF: C26H31N5O3
- MW: 461.56
Description
AZD0156 is potent, selective, and orally available inhibitor of ATM kinase. AZD0156 prevents DNA damage checkpoint activation, disrupts DNA damage repair, induces tumor cell apoptosis, and leads to cell death in ATM-overexpressing tumor cells. In addition, AZD0156 also sensitizes tumor cells to chemo- and radiotherapy.
More Information
| Parent CAS No. | 1821428-35-6 |
|---|---|
| Chemical Name | 8-(6-(3-(Dimethylamino)propoxy)pyridin-3-yl)-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]quinolin-2(3H)-one |
| MFCD | N.A. |
| Short Description | ATM inhibitor |
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